Pharmaceutical Chemistry Professional Research

Pharmaceutical chemistry is a profession that combines three major disciplines: basic sciences, biomedical sciences and pharmaceutical sciences.

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Clenbuterol - a drug for weight loss

Clenbuterol - a drug that is used in medicine for the treatment of bronchial asthma. In recent years, clenbuterol has been widely used in bodybuilding and fitness in relation to its ability to burn fat, so it is often used by athletes for weight loss and drying. Clenbuterol courses often include thyroxine and ketotifen to speed up the process of losing weight. Clenbuterol is not related to anabolic steroids and belongs to a group of agonists, which exert their physiological effects due to the excitation of beta-2 -adrenergic receptors, resulting in the sympathetic nervous system is activated and starts lipolysis. To purchase the needed prescription drug, but most pharmacies do not ask.

Several research papers have reported frequent ineligibility include clenbuterol in the sports supplements for fat burning.

The mechanism deystviyapravit
As beta-2 agonist, clenbuterol acts as zhiroszhigatel binding to beta- receptor type 2 in adipose and muscle tissue of the human body. Once coupled receptor clenbuterol, a cascade of biochemical reactions that lead to increased synthesis of cAMP (cyclic adenosine monophosphate). cAMP, in turn, activates enzymes which mobilize fatty acids from adipose (fat cells).

Anabolic and anti-catabolic effects of clenbuterol
Under the action of clenbuterol on beta-2-adrenergic presynaptic membrane increases the release of noradrenaline and adrenaline, which have potent fat burning effect. Clenbuterol increases the metabolic rate by 20-30 % from baseline.

Clenbuterol inhibits the activity of lipoprotein lipase, resulting in the deposition of fat in the adipose tissue becomes impossible. Acting beta-2-adrenergic receptors of the central nervous system, the drug increases the secretion of hormones by the thyroid gland - a natural body fat burners.

A unique feature of Clenbuterol is that it is not only a powerful fat burner, but also has a strong anti-catabolic effect, protecting the muscles from breaking down, which is very important during weight loss and drying in bodybuilding. Studies have shown that anti-catabolic effects of the drug caused by blocking Ca + + dependent and ubiquitin- proteasome proteolysis.

"Attention" New research in 2012 (Francesca Wannenes, Loretta Magni) confirms the ability of clenbuterol to block the mechanisms of muscle atrophy.

Due to the above-mentioned mechanisms of the drug has a moderate anabolic effect, as evidenced in animal experiments and practical applications in bodybuilding. Some authors (Yuri Bombel) claim that large doses of clenbuterol can have catabolic effects, however, this statement is not true. To do this, there is no physiological or practical justification.

Given the fact that the drug does not substantially interact with beta-1 adrenergic receptors occurs bronchiectasis and facilitating breathing, and also much lower frequency of side effects of the cardiovascular system as compared to non-selective agonist, such as ephedrine.

Pharma Chemicals

Research & Development

Our chemical development and manufacturing specialties include our Green Chemistry Toolbox for biocatalysis, homogenous catalysis and micro reactor technology with an integrated approach of chemistry and biotechnology.

Chemistry and Pharmacy

The pharmacy profession, exercised with the title Chemical - Pharmaceutical, is oriented toward science, technology and use of medicines in order to meet the needs of the population in this important aspect of health. Career Opportunities: These professionals can exercise independently, installing its own pharmacy or pharmaceutical laboratory.